Symptoms are not specific to Acute Lymphoblastic Leukemia (A.L.L), but as-well-as worsen to the point that medical help is sought.
They result from the lack of normal and healthy blood cells because they are crowded out by MALIGNANT and immature LEUKOCYTES .
Therefore, people with ALL experience symptoms from malfunctioning of their erythrocytes (red blood cells), leukocytes, and platelets.
Laboratory tests that might show abnormalities include blood count tests, renal function tests, electrolyte tests, and liver enzyme tests.
The signs and symptoms of ALL are variable but follow from bone marrow replacement and or organ infiltration.
- Generalized weakness and Fatigue
- Anemia.
- Frequent or unexplained fever and infection.
- Weight loss and/or loss of Appetite.
- Excessive and unexplained Bruising.
- Bone pain, joint pain (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow cavity).
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- Breathlessness.
- Enlarged Lymph Nodes, liver and/or spleen.
- Pitting Edema (swelling) in the lower limbs and/or abdomen.
- Petechiae, which are tiny red spots or lines in the skin due to low platelet levels
What is chemotherapy?
Chemotherapy (also called chemo) is a type of cancer treatment that uses drugs to destroy cancer cells.
How does chemotherapy work?
Chemotherapy works by stopping or slowing the growth of cancer cells, which grow and divide quickly. But it can also harm healthy cells that divide quickly, such as those that line your mouth and intestines or cause your hair to grow. Damage to healthy cells may cause side effects. Often, side effects get better or go away after chemotherapy is over.
What does chemotherapy do?
Depending on your type of cancer and how advanced it is, chemotherapy can:
Cure cancer - when chemotherapy destroys cancer cells to the point that your doctor can no longer detect them in your body and they will not grow back.
Control cancer - when chemotherapy keeps cancer from spreading, slows its growth, or destroys cancer cells that have spread to other parts of your body.
Ease cancer symptoms (also called palliative care) - when chemotherapy shrinks tumors that are causing pain or pressure.
How is chemotherapy used?
Sometimes, chemotherapy is used as the only cancer treatment. But more often, you will get chemotherapy along with surgery, radiation therapy, or biological therapy. Chemotherapy can:
Make a tumor smaller before surgery or radiation therapy. This is called neo-adjuvant chemotherapy.
Destroy cancer cells that may remain after surgery or radiation therapy. This is called adjuvant chemotherapy.
Help radiation therapy and biological therapy work better.
Destroy cancer cells that have come back (recurrent cancer) or spread to other parts of your body (metastatic cancer).
How does my doctor decide which chemotherapy drugs to use?
This choice depends on:
The type of cancer you have. Some types of chemotherapy drugs are used for many types of cancer. Other drugs are used for just one or two types of cancer.
Whether you have had chemotherapy before
Whether you have other health problems, such as diabetes or heart disease
Where do I go for chemotherapy?
You may receive chemotherapy during a hospital stay, at home, or in a doctor's office, clinic, or outpatient unit in a hospital (which means you do not have to stay overnight). No matter where you go for chemotherapy, your doctor and nurse will watch for side effects and make any needed drug changes.
How often will I receive chemotherapy?
Treatment schedules for chemotherapy vary widely. How often and how long you get chemotherapy depends on:
Your type of cancer and how advanced it is
The goals of treatment (whether chemotherapy is used to cure your cancer, control its growth, or ease the symptoms)
The type of chemotherapy
How your body reacts to chemotherapy
You may receive chemotherapy in cycles. A cycle is a period of chemotherapy treatment followed by a period of rest. For instance, you might receive 1 week of chemotherapy followed by 3 weeks of rest. These 4 weeks make up one cycle. The rest period gives your body a chance to build new healthy cells.
